It happened before 4:30 a.m. Tuesday in the northbound lanes at Exit 9, West Fordham Road.
The tanker lost control and overturned onto a car, spilling 2700 gallons of fuel across the highway.
All northbound lanes were closed for several hours as crews arrived, put sand on the roadway to contain the spill and worked to right the tanker.
Southbound lanes were not closed, but NewsCopter 7 found significant delays there as well, delays that extended to the Cross Bronx Expressway and the George Washington Bridge.
Motorists were advised to seek alternate routes.
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